Metabolism and functions of cyclic AMP in nerve ... (and) The role of macromolecules in neuronal function in aplysia
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Metabolism and functions of cyclic AMP in nerve ... (and) The role of macromolecules in neuronal function in aplysia by George I. Drummond

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Published by Pergamon in Oxford .
Written in English


Book details:

Edition Notes

Other titlesThe role of macromolecules in neuronal function in aplysia.
Statement(by) R. Price Peterson and Y. Peng Loh.
SeriesProgress in neurobiology -- 2:2
ContributionsPeterson, R. Price., Loh, Y. Peng.
The Physical Object
Paginationp. 119-203
Number of Pages203
ID Numbers
Open LibraryOL20331201M

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In addition, nerve growth factor does not alter the amounts of intracellular cyclic AMP during incubations up to 24 hr and does not stimulate adenylate cyclase in broken-cell preparations. Addition of theophylline, an inhibitor of phosphodiesterase, causes increases in intracellular levels of cyclic AMP but does not affect fiber by:   TM ROLE OF CYCLIC AMP-DEPENDENT PROTEIN KINASE IN THE CATECHOLAMINE MEDIATED REGULATION OF NERVE GROWTH FACTOR CONTAINED IN C6 GLIOMA CELLS J.F. Schwartz and E. Costa Laboratory of Preclinical Pharmacology, National Institute of Mental Health, Saint Elizabeths Hospital, Washington, D.C. ABSTRACT: Activation of the C6 Cited by: 1. Book: All Authors / Contributors: American College of Neuropsychopharmacology. ISBN: OCLC Number: Notes: Proceedings of a conference on the role of cyclic AMP in cell function held in San Diego, California, during the February annual meeting of the college. Description: pages illustrations. Series Title. 2. Neuronally Expressed Cyclic AMP Signaling Intermediaries Involved in Nerve Regeneration. Injury to the PNS switches the neuron's function from the provision of neurotransmission to the musculature back to its developmental role of axon growth [].After the PN is injured, its cytoplasm is exposed to the extracellular environment, permitting calcium and sodium ions to freely flow into the axon.

Glycogen metabolism is the best-studied example of the regulatory function of cAMP in the phosphorylation of phosphorylase b to phosphorylase a. The proven and hypothetical roles of cyclic nucleotides in human nonneurological disease have been described in detail elsewhere. 7,12,13,69,84,97,, The role of cyclic nucleotides in human. Instead, cyclic AMP stimulates a protein kinase cascade that ultimately leads to a cellular response. Cyclic AMP binds to protein kinase A, which then catalyzes the transfer of phosphate from ATP to a serine residue on a second enzyme, phosphorylase kinase, which itself transfers a phosphate to glycogen phosphorylase. Active glycogen phosphorylase then catalyzes the breakdown of glycogen to . Purchase Nutrition, Digestion, Metabolism - 1st Edition. Print Book & E-Book. ISBN ,   Cyclic AMP is a key regulator of intracellular functions and the metabolism. It’s a second-hand messenger in many biological processes, such as transportation of hormones and the activation of protein kinases. cAMP is derived from adenosine triphosphate (ATP), which is the energy currency of the cells.

This book is organized into nine chapters and begins with an overview of biochemical, morphological, and functional changes in the developing brain, as well as the underlying molecular basis of nerve differentiation and growth of the developing brain. An account of the concept of the cell cycle and its control is also given. Role in eukaryotic cells. Main article: function of cAMP-dependent protein kinase. cAMP is associated with kinases function in several biochemical processes, including the regulation of glycogen, sugar, and lipid metabolism. In eukaryotes, cyclic AMP works by activating protein kinase A (PKA, or cAMP-dependent protein kinase). The book further tackles calcium control of the intestinal microvillus cytoskeleton; the possible role of calmodulin in the regulation of insulin release and protein phosphorylation by calcium and cyclic AMP; and the role of calcium in mediating cellular functions important for . Cyclic AMP plays an important role in the regulation of metabolism generally. Emphasis in the present review has been placed on carbohydrate metabolism, but lipid metabolism has also been discussed to some extent.